Health & Fitness

What are the Risks and Benefits of a Bone Marrow Transplant?

Bone marrow, which is spongy in consistency, is found inside the bones of humans and animals. A bone marrow transplant is a procedure to replace the bone marrow that has been affected by infection, cancer, or chemotherapy.

The entire procedure is exceptionally intricate and involves transplanting blood stem cells. The stem cells travel toward the bone marrow, producing new blood cells and bone marrow.

The cost of bone marrow transplants in India is affordable. If you know someone looking forward to getting a bone marrow transplant, BLK-Max Super Speciality Hospital is the best.

Know the Benefits of Bone Marrow Transplant in India

The procedure of bone marrow transplantation is widely practiced to treat many diseases very effectively.

  • Severe aplastic Anaemia
  • Leukemias
  • Lymphomas
  • Solid tumor cancer
  • Deficiency disorders
  • Multiple myeloma

The effect of these diseases might vary from person to person. A bone marrow transplant might not be the right suit for everyone, so it is better to consult an expert.

Know the Risks of Bone Marrow Transplant

Besides providing benefits, a bone marrow transplant can pose certain risks and complications. But the dangers of the transplant will differ from person to person and various other factors like:

  • The regimen for preparation.
  • The type of bone marrow transplant.
  • The kind of disease requiring a bone marrow transplant.
  • Age and health of the recipient.
  • Presence of other risk factors and complications.
  • Issues with tissue matching between the donor and the recipient.

Let us now take a quick look at the risks that might arise due to a bone marrow transplant.

●      Severe Pain

The occurrence of severe pain during bone marrow transplantation is very commonly found. It mainly results in gastrointestinal irritation and mouth sores.

●      Multiple Infections

Severe bone marrow suppression will always lead to unexpected infections. Most infections are bacterial, whereas viral and fungal infections can be life-threatening.

●      Overloading of Fluid

The overloading of fluid might have high chances of leading to pneumonia, high blood pressure, and liver damage. This condition mainly happens because the kidneys cannot procedd the excessive fluid generated in the body due to medication.

●      Lower Count of Red Blood Cells and Platelets

Non-functioning bone marrow might cause anemia and thrombocytopenia, which can be dangerous. The low count of platelets might sometimes cause bleeding in the brain, lungs, and GI tract.

●      Respiratory Complications

The respiratory function might sometimes be compromised during a bone marrow transplant. Fluid overload, bleeding, or airway inflammation might cause life-threatening complications to the lungs and pulmonary system.

●      Failure of Graft

Graft failure is a substantial complication, and it might happen due to any recurrent disease or infection. Sometimes, the count of stem cells in the donated marrow is insufficient, causing engraftment.

●      Organ Damage

Bone marrow transplantation might have the chance to affect the heart and the liver during the process. There might be permanent or temporary damage by infection, high doses of chemotherapy, fluid overload, or infection.

●      Graft-versus-Host Disease

The GVHD can be a complicated, severe, and life-threatening disease caused by a bone marrow transplant. It usually happens when the immune system reacts unusually against the recipient’s tissues.

Here, the transplanted immune system attacks all the organs of the patient. The newly induced cells do not recognize the existing tissues, so it reacts.

But this condition can be cured with medicines so that the new cells stop attacking the existing ones. GVHD primarily attacks the lungs, GI tract, skin, and liver.

Bone Marrow Transplant – What are the Types?

A bone marrow transplant can be of various types that entirely depend on the donor and the recipient. The types of bone marrow transplantation are:

●      Allogeneic Bone Marrow Transplant

When the donor and the recipient share the same genetic type, an allogeneic bone marrow transplant is performed. The donor of this transplant is usually siblings and, at times, parents.

●      Autologous Bone Marrow Transplant

An autologous bone marrow transplant is performed when the donor and recipient are the same. The stem cells are harvested, stored, and placed back after intensive treatment.

●      Umbilical Cord Blood Transplant

The stem cells of the umbilical cord are very effective in treating cancer. Once an infant is delivered, the stem cells are collected and stored for producing mature stem cells.

To Conclude

The best allogeneic transplant hospital in India is BLK-Max Super Speciality Hospital. They provide the best treatment and ensure that no severe complications arise. Before undergoing a bone marrow transplant, it is always best to consult with a physician.

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